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chenodeoxycholic acid cdca group  (MedChemExpress)


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    MedChemExpress chenodeoxycholic acid cdca group
    Chenodeoxycholic Acid Cdca Group, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 36 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/chenodeoxycholic+acid+cdca+group/Chenodeoxycholic+Acid/pmc12692243-95-47-56
    Average 95 stars, based on 36 article reviews
    chenodeoxycholic acid cdca group - by Bioz Stars, 2026-09
    95/100 stars

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    Article Snippet: Subsequently, the cells were randomly divided into the nine groups: CON group (10% FBS), LPS group (1 μg/L; Cat No. L2630-10MG, Sigma), YXT drug serum group (10%), Cholic acid (CA) group (100 μg/mL; Cat. No. HY-N0324, MCE), Deoxycholic Acid (DCA) group (150 μg/mL; Cat. No. HY-N0593, MCE), Chenodeoxycholic Acid (CDCA) group (150 μg/mL; Cat. No. HY-76847, MCE), Lithocholic Acid (LCA) group (30 μg/mL; Cat. No. HY-B0172, MCE), TGR5 inhibitor group (100 μg/mL SBI-115; Cat. No. HY-111534, MCE), and TGR5 agonist group (100 μg/mL INT-77; Cat. No. HY-15677, MCE).



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    let cdca group  (TargetMol)
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    Intestinal FXR plays an important role in glucose metabolism in PCOS model mice . Mice were divided into 3 groups (LET, <t>LET+CDCA,</t> and LET+GUDCA) and were treated for 35 days to explore the effects of intestinal FXR (LET: 4, LET+CDCA: 7, and LET+GUDCA: 8). (A) Schematic representation of the experimental design. (B) GTT. (C) Fasting blood glucose. (D) Thirty minutes after glucose injection. (E) Mean blood glucose. (F) Area under the curve (AUC) of the GTT. (G) Fasting insulin. (H) HOMA-IR. (B-H) P values were determined by 1-way ANOVA with the least significant difference (LSD) multiple comparison post hoc test. P < 0.05 was considered statistically significant. CDCA, chenodeoxycholic acid; FXR, farnesoid X receptor; GTT, glucose tolerance test; GUDCA, glycoursodeoxycholic acid; HOMA-IR, homeostasis model assessment for insulin resistance index; LET, letrozole; PCOS, polycystic ovarian syndrome.
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    Intestinal FXR plays an important role in glucose metabolism in PCOS model mice . Mice were divided into 3 groups (LET, LET+CDCA, and LET+GUDCA) and were treated for 35 days to explore the effects of intestinal FXR (LET: 4, LET+CDCA: 7, and LET+GUDCA: 8). (A) Schematic representation of the experimental design. (B) GTT. (C) Fasting blood glucose. (D) Thirty minutes after glucose injection. (E) Mean blood glucose. (F) Area under the curve (AUC) of the GTT. (G) Fasting insulin. (H) HOMA-IR. (B-H) P values were determined by 1-way ANOVA with the least significant difference (LSD) multiple comparison post hoc test. P < 0.05 was considered statistically significant. CDCA, chenodeoxycholic acid; FXR, farnesoid X receptor; GTT, glucose tolerance test; GUDCA, glycoursodeoxycholic acid; HOMA-IR, homeostasis model assessment for insulin resistance index; LET, letrozole; PCOS, polycystic ovarian syndrome.

    Journal: Endocrinology

    Article Title: Intestinal Flora is a Key Factor in Insulin Resistance and Contributes to the Development of Polycystic Ovary Syndrome

    doi: 10.1210/endocr/bqab118

    Figure Lengend Snippet: Intestinal FXR plays an important role in glucose metabolism in PCOS model mice . Mice were divided into 3 groups (LET, LET+CDCA, and LET+GUDCA) and were treated for 35 days to explore the effects of intestinal FXR (LET: 4, LET+CDCA: 7, and LET+GUDCA: 8). (A) Schematic representation of the experimental design. (B) GTT. (C) Fasting blood glucose. (D) Thirty minutes after glucose injection. (E) Mean blood glucose. (F) Area under the curve (AUC) of the GTT. (G) Fasting insulin. (H) HOMA-IR. (B-H) P values were determined by 1-way ANOVA with the least significant difference (LSD) multiple comparison post hoc test. P < 0.05 was considered statistically significant. CDCA, chenodeoxycholic acid; FXR, farnesoid X receptor; GTT, glucose tolerance test; GUDCA, glycoursodeoxycholic acid; HOMA-IR, homeostasis model assessment for insulin resistance index; LET, letrozole; PCOS, polycystic ovarian syndrome.

    Article Snippet: Mice in the LET+CDCA group were administered LET and CDCA (Targetmol, catalog #T0847) at a dosage of 50 mg/kg/d ( ) once daily by oral gavage.

    Techniques: Injection, Comparison